Abstract Mucosal melanomas generally arise from mucosal epithelium lining the respiratory, alimentary, and genitourinary tracts and usually carry worse prognosis than cutaneous melanomas. Anorectal melanomas account for 50% of gastrointestinal tract melanomas and 0.3 to 1% of all malignant melanomas. There are no specific treatment guidelines due to the scarcity...
Evaluation of Treatment and Recurrence-Free Survival in Patients with Early HER2-Positive Breast Cancer: Real-Life Data Comparing Public and Private Healthcare
Abstract Introduction The present study was designed to compare the treatment provided in private and public health care facilities for women positive for early breast cancer of the human epidermal growth factor receptor 2 (HER2) subtype, who received anti-HER2 therapy in neoadjuvant or adjuvant settings, with an evaluation of the recurrence-free...
Abstract Objective To evaluate the technical notes (TNs) issued by the Center for Technical Support of the Judiciary (Núcleo de Apoio Técnico do Poder Judiciário, NAT-Jus, in Portuguese) of the Brazilian Ministry of Justice regarding lawsuits against the Brazilian Unified Health System (Sistema Único de Saúde, SUS, in Portuguese) concerning bladder/ureteral...
ABSTRACT The objective of this work is, through a literature review, to promote the debate on personalized medicine and acquire a broad view of the subject and its tools from the perspective of oncology, disseminate the topic, support, and encourage initiatives to implement its technologies in the Brazilian public healthcare...
ABSTRACT Penile melanoma is a rare event, responsible for less than 1.4% of penile cancers. In general, it is late diagnosed and the treatment is usually aggressive. The authors present a 66-year-old Caucasian man who had an ulcerated penile lesion for 1 year, diagnosed as melanoma after biopsy and treated...
ABSTRACT In December 2019, a novel coronavirus disease (COVID-19) emerged in Wuhan, a city in the Hubei, Province of China. It rapidly spread in an epidemic fashion throughout China, followed by rapid increasing number of cases in many countries throughout the world, including Brazil. It is expected that oncologic patients...
RESUMO Introdução: O carcinoma medular da tireoide (CMT) é um tumor neuroendócrino raro, e representa cerca de 3 a 10% dos carcinomas de tireoide. Entretanto, sua detecção e intervenção precoces podem modificar a evolução do CMT. Objetivo: Identificar a frequência do carcinoma medular de tireoide registrada em fontes institucionais (FI)...
ABSTRACT Objective: Data is lacking about FOLFIRINOX use for advanced pancreatic ductal adenocarcinoma in emerging countries. The objective of this study was to report outcomes of efficacy and safety in the setting of a South American institution. Methods: Patients treated with FOLFIRINOX for metastatic or locally advanced pancreatic cancer at...
The natural history of HER2-positive early breast was dramatically changed in 2005 by the results of 4 randomised phase III trials evaluating the combination of chemotherapy with adjuvant trastuzumab, the first drug in the anti-HER2 class. HERA, BCIRG-006, NCCTG 9831 and NSABP-B31 established 1 year of adjuvant trastuzumab as the...
ABSTRACT Introduction: Hepatocellular carcinoma (HCC) corresponds to 90% of primary malignant liver cell carcinomas and is a leading cause of cancer-related death worldwide. Objective: This compilation of cases aimed to identify evidence of correlation between anabolic androgen steroids (AAS) abuse for performance improvement by healthy subjects and HCC. Methods: We...
